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Banks Catherine M. Modeling and Simulation in the Medical Health Sciences


This edited book is divided into three parts: Fundamentals of Medical and Health Sciences Modeling and Simulation introduces modeling and simulation in the medical and health sciences; Medical and Health Sciences Models provides the theoretical underpinnings of medical and health sciences modeling; and Modeling and Simulation Applications in Medical and Health Sciences focuses on teaching, training, and research applications. The book begins with a general discussion of modeling and simulation from the modeling and simulation discipline perspective. This discussion grounds the reader in common terminology. It also relates this terminology to concepts found in the medical and health care (MHC) area to help bridge the gap between developers and MHC practitioners. Three distinct modes of modeling and simulation are described: live, constructive, and virtual. The live approach explains the concept of using real (live) people employing real equipment for training purposes. The constructive mode is a means of engaging medical modeling and simulation. In constructive simulation, simulated people and simulated equipment are developed to augment real-world conditions for training or experimentation purposes. The virtual mode is perhaps the most fascinating as virtual operating rooms and synthetic training environments are being produced for practitioners and educators at break-neck speed. In this mode, real people are employing simulated equipment to improve physical skills and decision-making ability.

7761.14 РУБ

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Banks Catherine M. Modeling and Simulation Fundamentals. Theoretical Underpinnings Practical Domains


An insightful presentation of the key concepts, paradigms, and applications of modeling and simulation Modeling and simulation has become an integral part of research and development across many fields of study, having evolved from a tool to a discipline in less than two decades. Modeling and Simulation Fundamentals offers a comprehensive and authoritative treatment of the topic and includes definitions, paradigms, and applications to equip readers with the skills needed to work successfully as developers and users of modeling and simulation. Featuring contributions written by leading experts in the field, the books fluid presentation builds from topic to topic and provides the foundation and theoretical underpinnings of modeling and simulation. First, an introduction to the topic is presented, including related terminology, examples of model development, and various domains of modeling and simulation. Subsequent chapters develop the necessary mathematical background needed to understand modeling and simulation topics, model types, and the importance of visualization. In addition, Monte Carlo simulation, continuous simulation, and discrete event simulation are thoroughly discussed, all of which are significant to a complete understanding of modeling and simulation. The book also features chapters that outline sophisticated methodologies, verification and validation, and the importance of interoperability. A related FTP site features color representations of the books numerous figures. Modeling and Simulation Fundamentals encompasses a comprehensive study of the discipline and is an excellent book for modeling and simulation courses at the upper-undergraduate and graduate levels. It is also a valuable reference for researchers and practitioners in the fields of computational statistics, engineering, and computer science who use statistical modeling techniques.

11087.34 РУБ

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David Pittenger J. Understanding and Conducting Research in the Health Sciences


A comprehensive introduction to behavioral and social science research methods in the health sciences Understanding and Conducting Research in the Health Sciences is designed to develop and facilitate the ability to conduct research and understand the practical value of designing, conducting, interpreting, and reporting behavioral and social science research findings in the health science and medical fields. The book provides complete coverage of the process behind these research methods, including information-gathering, decision formation, and results presentation. Examining the application of behavioral and social science research methodologies within the health sciences, the book focuses on implementing and developing relevant research questions, collecting and managing data, and communicating various research perspectives. An essential book for readers looking to possess an understanding of all aspects of conducting research in the health science field, Understanding and Conducting Research in the Health Sciences features: Various research designs that are appropriate for use in the health sciences, including single-participant, multi-group, longitudinal, correlational, and experimental designs Step-by-step coverage of single-factor and multifactor studies as well as single-subject and nonexperimental methods Accessible chapter explanations, real-world examples, and numerous illustrations throughout Guidance regarding how to write about research within the formatting styles of the American Medical Association and the American Psychological Association The book is an excellent educational resource for healthcare and health service practitioners and researchers who are interested in conducting and understanding behavioral and social science research done within the health sciences arena. The book is also a useful resource for students taking courses in the fields of medicine, public health, epidemiology, biostatistics, and the health sciences.

10727.86 РУБ

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S. Arifin M.Niaz Spatial Agent-Based Simulation Modeling in Public Health. Design, Implementation, and Applications for Malaria Epidemiology


Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology.

9647.09 РУБ

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Jerry Couretas M. An Introduction to Cyber Modeling and Simulation


Introduces readers to the field of cyber modeling and simulation and examines current developments in the US and internationally This book provides an overview of cyber modeling and simulation (M&S) developments. Using scenarios, courses of action (COAs), and current M&S and simulation environments, the author presents the overall information assurance process, incorporating the people, policies, processes, and technologies currently available in the field. The author ties up the various threads that currently compose cyber M&S into a coherent view of what is measurable, simulative, and usable in order to evaluate systems for assured operation. An Introduction to Cyber Modeling and Simulation provides the reader with examples of tools and technologies currently available for performing cyber modeling and simulation. It examines how decision-making processes may benefit from M&S in cyber defense. It also examines example emulators, simulators and their potential combination. The book also takes a look at corresponding verification and validation (V&V) processes, which provide the operational community with confidence in knowing that cyber models represent the real world. This book: Explores the role of cyber M&S in decision making Provides a method for contextualizing and understanding cyber risk Shows how concepts such the Risk Management Framework (RMF) leverage multiple processes and policies into a coherent whole Evaluates standards for pure IT operations, «cyber for cyber,» and operational/mission cyber evaluations—cyber for others Develops a method for estimating both the vulnerability of the system (i.e., time to exploit) and provides an approach for mitigating risk via policy, training, and technology alternatives Uses a model-based approach An Introduction to Cyber Modeling and Simulation is a must read for all technical professionals and students wishing to expand their knowledge of cyber M&S for future professional work.

8249.51 РУБ

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Roderick Melnik Mathematical and Computational Modeling. With Applications in Natural Social Sciences, Engineering, the Arts


Illustrates the application of mathematical and computational modeling in a variety of disciplines With an emphasis on the interdisciplinary nature of mathematical and computational modeling, Mathematical and Computational Modeling: With Applications in the Natural and Social Sciences, Engineering, and the Arts features chapters written by well-known, international experts in these fields and presents readers with a host of state-of-the-art achievements in the development of mathematical modeling and computational experiment methodology. The book is a valuable guide to the methods, ideas, and tools of applied and computational mathematics as they apply to other disciplines such as the natural and social sciences, engineering, and technology. Mathematical and Computational Modeling: With Applications in the Natural and Social Sciences, Engineering, and the Arts also features: Rigorous mathematical procedures and applications as the driving force behind mathematical innovation and discovery Numerous examples from a wide range of disciplines to emphasize the multidisciplinary application and universality of applied mathematics and mathematical modeling Original results on both fundamental theoretical and applied developments in diverse areas of human knowledge Discussions that promote interdisciplinary interactions between mathematicians, scientists, and engineers Mathematical and Computational Modeling: With Applications in the Natural and Social Sciences, Engineering, and the Arts is an ideal resource for professionals in various areas of mathematical and statistical sciences, modeling and simulation, physics, computer science, engineering, biology and chemistry, industrial, and computational engineering. The book also serves as an excellent textbook for graduate courses in mathematical modeling, applied mathematics, numerical methods, operations research, and optimization.

7714.01 РУБ

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Andreas Tolk The Profession of Modeling and Simulation. Discipline, Ethics, Education, Vocation, Societies, Economics


The definite guide to the theory, knowledge, technical expertise, and ethical considerations that define the M&S profession From traffic control to disaster management, supply chain analysis to military logistics, healthcare management to new drug discovery, modeling and simulation (M&S) has become an essential tool for solving countless real-world problems. M&S professionals are now indispensable to how things get done across virtually every aspect of modern life. This makes it all the more surprising that, until now, no effort has been made to systematically codify the core theory, knowledge, and technical expertise needed to succeed as an M&S professional. This book brings together contributions from experts at the leading edge of the modeling and simulation profession, worldwide, who share their priceless insights into issues which are fundamental to professional success and career development in this critically important field. Running as a common thread throughout the book is an emphasis on several key aspects of the profession, including the essential body of knowledge underlying the M&S profession; the technical discipline of M&S; the ethical standards that should guide professional conduct; and the economic and commercial challenges today’s M&S professionals face. • Demonstrates applications of M&S tools and techniques in a variety of fields—such as engineering, operations research, and cyber environments—with over 500 types of simulations • Highlights professional and academic aspects of the field, including preferred programming languages, professional academic and certification programs, and key international societies • Shows why M&S professionals must be fully versed in the theory, concepts, and tools needed to address the challenges of cyber environments The Profession of Modeling and Simulation is a valuable resource for M&S practitioners, developers, and researchers working in industry and government. Simulation professionals, including administrators, managers, technologists, faculty members, and scholars within the physical sciences, life sciences, and engineering fields will find it highly useful, as will students planning to pursue a career in the M&S profession. “ …nearly three dozen experts in Modeling and Simulation (M&S) come together to make a compelling case for the recognition of M&S as a profession… Important reading for anyone seeking to elevate the standing of this vital field.” Alfred (Al) Grasso, President & CEO, The MITRE Corporation Andreas Tolk, PhD, is Technology Integrator for the Modeling, Simulation, Experimentation, and Analytics Division of The MITRE Corporation, an adjunct professor in the Department of Engineering Management and Systems Engineering and the Department for Modeling, Simulation, and Visualization Engineering at Old Dominion University, and an SCS fellow. Tuncer Ören, PhD, is Professor Emeritus of Computer Science at the University of Ottawa. He is an SCS fellow and an inductee to SCS Modeling and Simulation Hall of Fame. His research interests include advancing methodologies, ethics, body of knowledge, and terminology of modeling and simulation.

10419.59 РУБ

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DongHun Kang Modeling and Simulation of Discrete Event Systems


Computer modeling and simulation (M&S) allows engineers to study and analyze complex systems. Discrete-event system (DES)-M&S is used in modern management, industrial engineering, computer science, and the military. As computer speeds and memory capacity increase, so DES-M&S tools become more powerful and more widely used in solving real-life problems. Based on over 20 years of evolution within a classroom environment, as well as on decades-long experience in developing simulation-based solutions for high-tech industries, Modeling and Simulation of Discrete-Event Systems is the only book on DES-M&S in which all the major DES modeling formalisms – activity-based, process-oriented, state-based, and event-based – are covered in a unified manner: A well-defined procedure for building a formal model in the form of event graph, ACD, or state graph Diverse types of modeling templates and examples that can be used as building blocks for a complex, real-life model A systematic, easy-to-follow procedure combined with sample C# codes for developing simulators in various modeling formalisms Simple tutorials as well as sample model files for using popular off-the-shelf simulators such as SIGMA®, ACE®, and Arena® Up-to-date research results as well as research issues and directions in DES-M&S Modeling and Simulation of Discrete-Event Systems is an ideal textbook for undergraduate and graduate students of simulation/industrial engineering and computer science, as well as for simulation practitioners and researchers.

9493.32 РУБ

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Muhammad Rafique, Sikander M. Mirza, Nasir Mirza Sensitivity Analysis of Corrosion Product Activity


Sikander M. Mirza He did his PhD from Purdue University, USA in 1990. He is professor in the Department of Physics & Applied Mathematics, at Pakistan Institute of Engineering & Applied Sciences. He has served as Head of the Department and currently serving as Dean of Faculty of Applied Sciences at PIEAS. His main research interests include Computational Physics, Modeling & Simulation, Radiation Physics and Advanced Numerical Techniques. He has published numerous scientific and technical journal articles in several areas including Numerical Methods, Computational & Simulation Physics and Applied Physics. Nasir M. Mirza He did his PhD from Purdue University, USA in 1989 and has been associated with Pakistan Institute of Engineering & Applied Sciences for over 15 year as professor of physics & applied mathematics. He has also served as a Dean Research at the PIEAS and currently chairs the Department. His main research interests include Modeling & Simulation, Computational Physics, reactor physics and Stochastic processes. He has published over 50 technical papers in various highly reputed international scientific & technical journals.

8789 РУБ

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Manuel Rossetti D. Simulation Modeling and Arena


Emphasizes a hands-on approach to learning statistical analysis and model building through the use of comprehensive examples, problems sets, and software applications With a unique blend of theory and applications, Simulation Modeling and Arena®, Second Edition integrates coverage of statistical analysis and model building to emphasize the importance of both topics in simulation. Featuring introductory coverage on how simulation works and why it matters, the Second Edition expands coverage on static simulation and the applications of spreadsheets to perform simulation. The new edition also introduces the use of the open source statistical package, R, for both performing statistical testing and fitting distributions. In addition, the models are presented in a clear and precise pseudo-code form, which aids in understanding and model communication. Simulation Modeling and Arena, Second Edition also features: Updated coverage of necessary statistical modeling concepts such as confidence interval construction, hypothesis testing, and parameter estimation Additional examples of the simulation clock within discrete event simulation modeling involving the mechanics of time advancement by hand simulation A guide to the Arena Run Controller, which features a debugging scenario New homework problems that cover a wider range of engineering applications in transportation, logistics, healthcare, and computer science A related website with an Instructor’s Solutions Manual, PowerPoint® slides, test bank questions, and data sets for each chapter Simulation Modeling and Arena, Second Edition is an ideal textbook for upper-undergraduate and graduate courses in modeling and simulation within statistics, mathematics, industrial and civil engineering, construction management, business, computer science, and other departments where simulation is practiced. The book is also an excellent reference for professionals interested in mathematical modeling, simulation, and Arena.

10033.71 РУБ

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MOHSEN GUIZANI Network Modeling and Simulation. A Practical Perspective


Network Modeling and Simulation is a practical guide to using modeling and simulation to solve real-life problems. The authors give a comprehensive exposition of the core concepts in modeling and simulation, and then systematically address the many practical considerations faced by developers in modeling complex large-scale systems. The authors provide examples from computer and telecommunication networks and use these to illustrate the process of mapping generic simulation concepts to domain-specific problems in different industries and disciplines. Key features: Provides the tools and strategies needed to build simulation models from the ground up rather than providing solutions to specific problems. Includes a new simulation tool, CASiNO built by the authors. Examines the core concepts of systems simulation and modeling. Presents code examples to illustrate the implementation process of commonly encountered simulation tasks. Offers examples of industry-standard modeling methodology that can be applied in steps to tackle any modeling problem in practice.

8334.94 РУБ

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Bryan Woodward m-Health. Fundamentals and Applications


Addresses recent advances from both the clinical and technological perspectives to provide a comprehensive presentation of m-Health This book introduces the concept of m-Health, first coined by Robert S. H. Istepanian in 2003. The evolution of m-Health since then—how it was transformed from an academic concept to a global healthcare technology phenomenon—is discussed. Afterwards the authors describe in detail the basics of the three enabling scientific technological elements of m-Health (sensors, computing, and communications), and how each of these key ingredients has evolved and matured over the last decade. The book concludes with detailed discussion of the future of m-Health and presents future directions to potentially shape and transform healthcare services in the coming decades. In addition, this book: Discusses the rapid evolution of m-Health in parallel with the maturing process of its enabling technologies, from bio-wearable sensors to the wireless and mobile communication technologies from IOT to 5G systems and beyond Includes clinical examples and current studies, particularly in acute and chronic disease management, to illustrate some of the relevant medical aspects and clinical applications of m-Health Describes current m-Health ecosystems and business models Covers successful applications and deployment examples of m-Health in various global health settings, particularly in developing countries

9647.09 РУБ

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William Kasch An Introduction to Network Modeling and Simulation for the Practicing Engineer


This book provides the practicing engineer with a concise listing of commercial and open-source modeling and simulation tools currently available including examples of implementing those tools for solving specific Modeling and Simulation examples. Instead of focusing on the underlying theory of Modeling and Simulation and fundamental building blocks for custom simulations, this book compares platforms used in practice, and gives rules enabling the practicing engineer to utilize available Modeling and Simulation tools. This book will contain insights regarding common pitfalls in network Modeling and Simulation and practical methods for working engineers.

6093.59 РУБ

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Raid Al-Aomar Process Simulation Using WITNESS


Teaches basic and advanced modeling and simulation techniques to both undergraduate and postgraduate students and serves as a practical guide and manual for professionals learning how to build simulation models using WITNESS, a free-standing software package. This book discusses the theory behind simulation and demonstrates how to build simulation models with WITNESS. The book begins with an explanation of the concepts of simulation modeling and a “guided tour” of the WITNESS modeling environment. Next, the authors cover the basics of building simulation models using WITNESS and modeling of material-handling systems. After taking a brief tour in basic probability and statistics, simulation model input analysis is then examined in detail, including the importance and techniques of fitting closed-form distributions to observed data. Next, the authors present simulation output analysis including determining run controls and statistical analysis of simulation outputs and show how to use these techniques and others to undertake simulation model verification and validation. Effective techniques for managing a simulation project are analyzed, and case studies exemplifying the use of simulation in manufacturing and services are covered. Simulation-based optimization methods and the use of simulation to build and enhance lean systems are then discussed. Finally, the authors examine the interrelationships and synergy between simulation and Six Sigma. Emphasizes real-world applications of simulation modeling in both services and manufacturing sectors Discusses the role of simulation in Six Sigma projects and Lean Systems Contains examples in each chapter on the methods and concepts presented Process Simulation Using WITNESS is a resource for students, researchers, engineers, management consultants, and simulation trainers.

11190.63 РУБ

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Andreas Tolk Modeling and Simulation Support for System of Systems Engineering Applications


“…a much-needed handbook with contributions from well-chosen practitioners. A primary accomplishment is to provide guidance for those involved in modeling and simulation in support of Systems of Systems development, more particularly guidance that draws on well-conceived academic research to define concepts and terms, that identifies primary challenges for developers, and that suggests fruitful approaches grounded in theory and successful examples.” Paul Davis, The RAND Corporation Modeling and Simulation Support for System of Systems Engineering Applications provides a comprehensive overview of the underlying theory, methods, and solutions in modeling and simulation support for system of systems engineering. Highlighting plentiful multidisciplinary applications of modeling and simulation, the book uniquely addresses the criteria and challenges found within the field. Beginning with a foundation of concepts, terms, and categories, a theoretical and generalized approach to system of systems engineering is introduced, and real-world applications via case studies and examples are presented. A unified approach is maintained in an effort to understand the complexity of a single system as well as the context among other proximate systems. In addition, the book features: Cutting edge coverage of modeling and simulation within the field of system of systems, including transportation, system health management, space mission analysis, systems engineering methodology, and energy State-of-the-art advances within multiple domains to instantiate theoretic insights, applicable methods, and lessons learned from real-world applications of modeling and simulation The challenges of system of systems engineering using a systematic and holistic approach Key concepts, terms, and activities to provide a comprehensive, unified, and concise representation of the field A collection of chapters written by over 40 recognized international experts from academia, government, and industry A research agenda derived from the contribution of experts that guides scholars and researchers towards open questions Modeling and Simulation Support for System of Systems Engineering Applications is an ideal reference and resource for academics and practitioners in operations research, engineering, statistics, mathematics, modeling and simulation, and computer science. The book is also an excellent course book for graduate and PhD-level courses in modeling and simulation, engineering, and computer science.

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Andreas Tolk Engineering Principles of Combat Modeling and Distributed Simulation


Explore the military and combat applications of modeling and simulation Engineering Principles of Combat Modeling and Distributed Simulation is the first book of its kind to address the three perspectives that simulation engineers must master for successful military and defense related modeling: the operational view (what needs to be modeled); the conceptual view (how to do combat modeling); and the technical view (how to conduct distributed simulation). Through methods from the fields of operations research, computer science, and engineering, readers are guided through the history, current training practices, and modern methodology related to combat modeling and distributed simulation systems. Comprised of contributions from leading international researchers and practitioners, this book provides a comprehensive overview of the engineering principles and state-of-the-art methods needed to address the many facets of combat modeling and distributed simulation and features the following four sections: Foundations introduces relevant topics and recommended practices, providing the needed basis for understanding the challenges associated with combat modeling and distributed simulation. Combat Modeling focuses on the challenges in human, social, cultural, and behavioral modeling such as the core processes of «move, shoot, look, and communicate» within a synthetic environment and also equips readers with the knowledge to fully understand the related concepts and limitations. Distributed Simulation introduces the main challenges of advanced distributed simulation, outlines the basics of validation and verification, and exhibits how these systems can support the operational environment of the warfighter. Advanced Topics highlights new and developing special topic areas, including mathematical applications fo combat modeling; combat modeling with high-level architecture and base object models; and virtual and interactive digital worlds. Featuring practical examples and applications relevant to industrial and government audiences, Engineering Principles of Combat Modeling and Distributed Simulation is an excellent resource for researchers and practitioners in the fields of operations research, military modeling, simulation, and computer science. Extensively classroom tested, the book is also ideal for courses on modeling and simulation; systems engineering; and combat modeling at the graduate level.

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Josh Laurito Financial Simulation Modeling in Excel. A Step-by-Step Guide


Ive worked with simulation in business for over 20 years, and Allman really nails it with this book. I admit that I own his previous book on structured finance cash flows, but I was surprised by what I found in here. He addresses the fundamental questions of how decision makers react to simulations and his read was very much in accordance with what Ive experienced myself. When it came to the nuts and bolts of describing the different types of simulation analysis the book becomes incredibly detailed. There is working code and models for a fantastic array of the most common simulation problems. If youre so inclined, the book very carefully steps through the tricky math needed to really understand the theory behind stochastic modeling in finance. If youre preparing models that include any kind of randomization or stochastic modeling component, this book is a must-read, a tremendous value and time-saver. – David Brode of The Brode Group A practical guide to understanding and implementing financial simulation modeling As simulation techniques become more popular among the financial community and a variety of sub-industries, a thorough understanding of theory and implementation is critical for practitioners involved in portfolio management, risk management, pricing, and capital budgeting. Financial Simulation Modeling in Excel contains the information you need to make the most informed decisions possible in your professional endeavors. Financial Simulation Modeling in Excel contains a practical, hands-on approach to learning complex financial simulation methodologies using Excel and VBA as a medium. Crafted in an easy to understand format, this book is suitable for anyone with a basic understanding of finance and Excel. Filled with in-depth insights and expert advice, each chapter takes you through the theory behind a simulation topic and the implementation of that same topic in Excel/VBA in a step-by-step manner. Organized in an easy-to-follow fashion, this guide effectively walks you through the process of creating and implementing risk models in Excel A companion website contains all the Excel models risk experts and quantitative analysts need to practice and confirm their results as they progress Keith Allman is the author of other successful modeling books, including Corporate Valuation Modeling and Modeling Structured Finance Cash Flows with Microsoft Excel Created for those with some background in finance and experience in Excel, this reliable resource shows you how to effectively perform sound financial simulation modeling, even if youve yet to do extensive modeling up to this point in your professional or academic career.

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John Sokolowski A. The Digital Patient. Advancing Healthcare, Research, and Education


A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

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Professor Caers Jef Modeling Uncertainty in the Earth Sciences


Modeling Uncertainty in the Earth Sciences highlights the various issues, techniques and practical modeling tools available for modeling the uncertainty of complex Earth systems and the impact that it has on practical situations. The aim of the book is to provide an introductory overview which covers a broad range of tried-and-tested tools. Descriptions of concepts, philosophies, challenges, methodologies and workflows give the reader an understanding of the best way to make decisions under uncertainty for Earth Science problems. The book covers key issues such as: Spatial and time aspect; large complexity and dimensionality; computation power; costs of engineering the Earth; uncertainty in the modeling and decision process. Focusing on reliable and practical methods this book provides an invaluable primer for the complex area of decision making with uncertainty in the Earth Sciences.

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Rachel Allen How to Complete a PhD in the Medical and Clinical Sciences


How to Complete a PhD in the Medical and Clinical Sciences provides fresh insight into the PhD process and a concise framework to aid current and prospective students undertaking research in the medical and clinical sciences. Filled with useful hints, tips, and practical guidance, the book covers key topics relevant to a PhD researcher such as publishing and presenting, core principles and techniques in medical science, dealing with common pitfalls, and how to write up and move on. Featuring contributions from authors with experience across the PhD research career spectrum, How to Complete a PhD in the Medical and Clinical Sciences is an invaluable resource for those undertaking their doctoral studies.

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Reif B. A.Pettersson Statistical Theory and Modeling for Turbulent Flows


Providing a comprehensive grounding in the subject of turbulence, Statistical Theory and Modeling for Turbulent Flows develops both the physical insight and the mathematical framework needed to understand turbulent flow. Its scope enables the reader to become a knowledgeable user of turbulence models; it develops analytical tools for developers of predictive tools. Thoroughly revised and updated, this second edition includes a new fourth section covering DNS (direct numerical simulation), LES (large eddy simulation), DES (detached eddy simulation) and numerical aspects of eddy resolving simulation. In addition to its role as a guide for students, Statistical Theory and Modeling for Turbulent Flows also is a valuable reference for practicing engineers and scientists in computational and experimental fluid dynamics, who would like to broaden their understanding of fundamental issues in turbulence and how they relate to turbulence model implementation. Provides an excellent foundation to the fundamental theoretical concepts in turbulence. Features new and heavily revised material, including an entire new section on eddy resolving simulation. Includes new material on modeling laminar to turbulent transition. Written for students and practitioners in aeronautical and mechanical engineering, applied mathematics and the physical sciences. Accompanied by a website housing solutions to the problems within the book.

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El-Bendary M. a. Kassem Wpans Technologies Modeling and Simulation


The wireless personal area networks play essential role within the advanced wirless technologies applications. the bluetooth is the earlier WPANs technologies, its the gate of personal communications development. This book presents the WPAN studying and its analytical and simulation steps. It also focuses on the error control utilizing in the WPANs networks. The computer simulation of standard and another channel coding schemes over different communications channels is dicussed in the book.

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Khaled Gharaibeh M. Nonlinear Distortion in Wireless Systems. Modeling and Simulation with MATLAB


This book covers the principles of modeling and simulation of nonlinear distortion in wireless communication systems with MATLAB simulations and techniques In this book, the author describes the principles of modeling and simulation of nonlinear distortion in single and multichannel wireless communication systems using both deterministic and stochastic signals. Models and simulation methods of nonlinear amplifiers explain in detail how to analyze and evaluate the performance of data communication links under nonlinear amplification. The book addresses the analysis of nonlinear systems with stochastic inputs and establishes the performance metrics of communication systems with regard to nonlinearity. In addition, the author also discusses the problem of how to embed models of distortion in system-level simulators such as MATLAB and MATLAB Simulink and provides practical techniques that professionals can use on their own projects. Finally, the book explores simulation and programming issues and provides a comprehensive reference of simulation tools for nonlinearity in wireless communication systems. Key Features: Covers the theory, models and simulation tools needed for understanding nonlinearity and nonlinear distortion in wireless systems Presents simulation and modeling techniques for nonlinear distortion in wireless channels using MATLAB Uses random process theory to develop simulation tools for predicting nonlinear system performance with real-world wireless communication signals Focuses on simulation examples of real-world communication systems under nonlinearity Includes an accompanying website containing MATLAB code This book will be an invaluable reference for researchers, RF engineers, and communication system engineers working in the field. Graduate students and professors undertaking related courses will also find the book of interest.

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Khaled Gharaibeh M. Nonlinear Distortion in Wireless Systems. Modeling and Simulation with MATLAB


This book covers the principles of modeling and simulation of nonlinear distortion in wireless communication systems with MATLAB simulations and techniques In this book, the author describes the principles of modeling and simulation of nonlinear distortion in single and multichannel wireless communication systems using both deterministic and stochastic signals. Models and simulation methods of nonlinear amplifiers explain in detail how to analyze and evaluate the performance of data communication links under nonlinear amplification. The book addresses the analysis of nonlinear systems with stochastic inputs and establishes the performance metrics of communication systems with regard to nonlinearity. In addition, the author also discusses the problem of how to embed models of distortion in system-level simulators such as MATLAB and MATLAB Simulink and provides practical techniques that professionals can use on their own projects. Finally, the book explores simulation and programming issues and provides a comprehensive reference of simulation tools for nonlinearity in wireless communication systems. Key Features: Covers the theory, models and simulation tools needed for understanding nonlinearity and nonlinear distortion in wireless systems Presents simulation and modeling techniques for nonlinear distortion in wireless channels using MATLAB Uses random process theory to develop simulation tools for predicting nonlinear system performance with real-world wireless communication signals Focuses on simulation examples of real-world communication systems under nonlinearity Includes an accompanying website containing MATLAB code This book will be an invaluable reference for researchers, RF engineers, and communication system engineers working in the field. Graduate students and professors undertaking related courses will also find the book of interest.

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Mike Davis How to Teach Using Simulation in Healthcare


How to Teach Using Simulation in Healthcare provides an ideal introduction and easy-to-use guide to simulation in medical education. Written by a team of experienced medical educators, this practical text – packed full of case examples and tips – is underpinned by the theory of simulation in education, and explores how to integrate simulation into teaching. Key topics include: Use of low, medium and high fidelity equipment Issues of simulation mapping and scenario design Role of human factors Formative and summative assessment New social media and technologies Detailed explorations of some examples of simulation. How to Teach Using Simulation in Healthcare is invaluable reading for all healthcare professionals interested and involved in the origins, theoretical underpinnings, and design implications of the use of simulation in medical education.

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David Machin Medical Statistics. A Textbook for the Health Sciences


Provides students and practitioners with a clear, concise introduction to the statistics they will come across in their regular reading of clinical papers. Written by three experts with wide teaching and consulting experience, Medical Statistics: A Textbook for the Health Sciences, Fourth Edition: Assumes no prior knowledge of statistics Covers all essential statistical methods Completely revised, updated and expanded Includes numerous examples and exercises on the interpretation of the statistics in papers published in medical journals From the reviews of the previous edition: «The book has several excellent features: it is written by statisticians, is.... well presented, is well referenced.... and is short.» THE LANCET «Many statisticians are concerned at the generally poor standard of statistics in papers published in medical journals. Perhaps this could be remedied if more research workers would spare a few hours to read through Campbell and Machins book.» BRITISH MEDICAL JOURNAL «… a simple, interesting and insightful introduction to medical statistics… highly recommended.» STATISTICAL METHODS IN MEDICAL RESEARCH «Campbell and Machin found the golden mean… this book can be recommended for all students and all medical researchers.» ISCB NEWSLETTER

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Venkatapuram Sridhar Health Justice. An Argument from the Capabilities Approach


Social factors have a powerful influence on human health and longevity. Yet the social dimensions of health are often obscured in public discussions due to the overwhelming focus in health policy on medical care, individual-level risk factor research, and changing individual behaviours. Likewise, in philosophical approaches to health and social justice, the debates have largely focused on rationing problems in health care and on personal responsibility. However, a range of events over the past two decades such as the study of modern famines, the global experience of HIV/AIDS, the international women’s health movement, and the flourishing of social epidemiological research have drawn attention to the robust relationship between health and broad social arrangements. In Health Justice, Sridhar Venkatapuram takes up the problem of identifying what claims individuals have in regard to their health in modern societies and the globalized world. Recognizing the social bases of health and longevity, Venkatapuram extends the ‘Capabilities Approach’ of Amartya Sen and Martha Nussbaum into the domain of health and health sciences. In so doing, he formulates an inter-disciplinary argument that draws on the natural and social sciences as well as debates around social justice to argue for every human being’s moral entitlement to a capability to be healthy. An ambitious integration of the health sciences and the Capabilities Approach, Health Justice aims to provide a concrete ethical grounding for the human right to health, while advancing the field of health policy and placing health at the centre of social justice theory. With a foreword by Sir Michael Marmot, chair of the WHO Commission on the Social Determinants of Health.

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James Nutaro J. Building Software for Simulation. Theory and Algorithms, with Applications in C++


A unique guide to the design and implementation of simulation software This book offers a concise introduction to the art of building simulation software, collecting the most important concepts and algorithms in one place. Written for both individuals new to the field of modeling and simulation as well as experienced practitioners, this guide explains the design and implementation of simulation software used in the engineering of large systems while presenting the relevant mathematical elements, concept discussions, and code development. The book approaches the topic from the perspective of Zeiglers theory of modeling and simulation, introducing the theorys fundamental concepts and showing how to apply them to engineering problems. Readers will learn five necessary skills for building simulations of complicated systems: Working with fundamental abstractions for simulating dynamic systems Developing basic simulation algorithms for continuous and discrete event models Combining continuous and discrete event simulations into a coherent whole Applying strategies for testing a simulation Understanding the theoretical foundations of the modeling constructs and simulation algorithms The central chapters of the book introduce, explain, and demonstrate the elements of the theory that are most important for building simulation tools. They are bracketed by applications to robotics, control and communications, and electric power systems; these comprehensive examples clearly illustrate how the concepts and algorithms are put to use. Readers will explore the design of object-oriented simulation programs, simulation using multi-core processors, and the integration of simulators into larger software systems. The focus on software makes this book particularly useful for computer science and computer engineering courses in simulation that focus on building simulators. It is indispensable reading for undergraduate and graduate students studying modeling and simulation, as well as for practicing scientists and engineers involved in the development of simulation tools.

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Jennifer Cleland Researching Medical Education


Researching Medical Education is an authoritative guide to excellence in educational research in the health professions. Presented by the Association for the Study of Medical Education and the Association for Medical Education in Europe, Researching Medical Education includes contributions from a team of international clinicians and non-clinical researchers in health education, representing a range of disciplines and backgrounds. This accessible reference provides readers with the basic building blocks of research, introduces a range of theories and how to use them, illustrates a diversity of methods and their use, and gives guidance on practical researcher development. By linking theory and design and methods across the health profession education research spectrum, this book supports the improvement of quality, capacity building and knowledge generation. Researching Medical Education is the ideal resource for anyone researching health education, from undergraduate, through postgraduate training, to continuing professional development.

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